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Portable system for continuous ex vivo measurements of lactate
H Håkanson1, M Kyröläinen, B Mattiasson
1Department of Biotechnology, Chemical Centre, Lund, Sweden.
Biosensors & Bioelectronics
|January 1, 1993
Abstract:
The lactate profile in serum was monitored continuously in volunteers under physical exercise on a test bicycle. The assay was operated ex vivo by means of continuous sampling through a coaxial catheter. After dialysis online, lactate was converted by means of lactate oxidase immobilized to porous glass, and the depletion of oxygen was registered by means of a Clark electrode. Good agreement between the continuous monitoring and off-line analyses was found.