Effect of imidocarb dipropionate and hemicastration on spermatogenesis in pony stallions

The effect of imidocarb dipropionate [3, 3' bis-(2-imidazolin-2-yl) carbanilide dipropionate] on spermatogenesis in 3 pony stallions was studied. The drug alone had no deleterious effect on spermatogenesis when given intramuscularly 4 times at a dosage level of 4 mg/kg at 72-hour intervals. Hemicastration, with or without subsequent drug treatment, caused almost complete cessation of spermatogenesis 30 days after the operation.