Spinal fluid pleocytosis in acute posterior multifocal placoid pigment epitheliopathy

Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a disorder of the fundus frequently characterized by sudden onset of bilateral, marked visual loss associated with yellowish-white, ill-defined placoid lesions of the retina. Most cases show a rapid resolution with restoration of vision to normal or near-normal levels. We evaluated an 11-year-old boy with presumed APMPPE who showed a mononuclear cell pleocytosis on spinal fluid examination.