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Susceptibility of Propionibacterium acnes to seventeen antibiotics
Antimicrobial Agents and Chemotherapy
|January 1, 1977
Abstract:
The in vitro susceptibility of 96 isolates of Propionibacterium acnes to 17 antibiotics was determined by utilizing an agar dilution technique. With the exception of the aminoglycosides, these organisms are susceptible to virtually all of the commonly used antimicrobial agents.
Insights
Propionibacterium acnes, a common bacterium, shows susceptibility to most antibiotics tested. Aminoglycosides were the exception, indicating potential resistance patterns for this antibiotic class in P. acnes infections.
Area of Science:
- Microbiology
- Antimicrobial Resistance
- Clinical Research
Background:
- Propionibacterium acnes is a bacterium implicated in various infections.
- Understanding antibiotic susceptibility is crucial for effective treatment strategies.
Purpose of the Study:
- To determine the in vitro antibiotic susceptibility profile of Propionibacterium acnes isolates.
- To identify which commonly used antimicrobial agents are effective against P. acnes.
Main Methods:
- Agar dilution technique was employed to test susceptibility.
- 96 isolates of Propionibacterium acnes were analyzed.
- 17 different antibiotics were evaluated against the bacterial isolates.
Main Results:
- Propionibacterium acnes demonstrated susceptibility to most tested antibiotics.
- Aminoglycosides were found to be an exception, showing limited efficacy.
- The study highlights broad susceptibility except for specific antibiotic classes.
Conclusions:
- Most common antimicrobial agents are effective against Propionibacterium acnes in vitro.
- Aminoglycosides may not be a suitable treatment option for P. acnes infections based on these findings.