Experience with high dose chemotherapy and autologous bone marrow transplantation in testicular cancer
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Updated: Aug 14, 2026
11:25
Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
Published on: April 1, 2015
Journal Belge De Radiologie
|March 1, 1993
Abstract:
Carboplatin based HDCT followed by ABMT produces reasonable response rates (40-60%) and some durable remissions in patients with advanced and cisplatin resistant testicular cancer. Patients eligible for such an approach are those with primary refractory or recurrent disease and low probability for salvage by conventional dose regimens. The use of recombinant human growth factors and peripheral stem cell transplantation will probably reduce the toxicity and mortality of HDCT.
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01:21Stem Cell Therapy for Tissue Regeneration
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
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01:22Bone Marrow Sampling and Transplants
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
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