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p53 protein expression in Reed-Sternberg cells of Hodgkin's disease
R K Gupta1, A J Norton, T A Lister
1ICRF Department of Medical Oncology, St. Bartholomew's Hospital, London, England, UK.
Leukemia
|August 1, 1993
Abstract:
Hodgkin's disease (HD) is perceived to be a malignant disease of the lymphoid system. One of the main obstacles into the investigation of the cell biology of Hodgkin's disease is the relative paucity of Reed-Sternberg cells (or variants), the presumed neoplastic component of this condition, which often make up less than 1% of the total cell number.