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Prenatal D1, D1b and D3 dopamine receptor gene expression in the rat forebrain: detection by reverse polymerase chain
M A Cadoret1, M Jaber, B Bloch
1URA CNRS 1200, Laboratoire d'Histologie-Embryologie, UFR II, Université de Bordeaux II, France.
Neuroscience Letters
|May 28, 1993
Abstract:
Three dopamine receptor mRNAs were detected by reverse polymerase chain reaction in the rat forebrain during ontogeny. The D1 receptor mRNA gave a faint signal from gestational day 11 (G11) on, while the D1b receptor was not detectable before G12. The D3 receptor mRNA was slightly expressed at G11 and clearly present at G14. Our results show that these mRNAs are present at early stages of fetal life, each one with its specific time of appearance.