Decreased basal tear production associated with general anesthesia

Area of Science:

• Ophthalmology
• Anesthesiology

Background:

• Basal tear production is crucial for ocular surface health.
• General anesthesia can potentially impact physiological functions, including tear secretion.

Purpose of the Study:

• To investigate the effect of general surgical anesthesia on basal tear production.
• To evaluate the impact of premedication on tear secretion.

Main Methods:

• Basal tear production was measured using standardized Schirmer strips.
• Topical anesthesia (0.5% proparacaine hydrochloride) was employed.
• 20 patients undergoing general anesthesia were studied.

Main Results:

• Systemic diazepam and atropine sulfate did not affect basal tear production.
• General anesthesia caused a significant decrease in basal tear production at 10, 30, and 60 minutes post-induction.
• Tear production levels were notably depressed during the anesthetic period.

Conclusions:

• General anesthesia adversely affects basal tear production.
• Ocular surface protection strategies are essential during general anesthesia.
• Recommendations include artificial tear use and corneal protection measures.