Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Course and outcome in panic disorder

M B Keller1, D L Hanks

  • 1Department of Psychiatry and Human Behavior, Brown University Providence, RI.

Progress in Neuro-Psychopharmacology & Biological Psychiatry
|July 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A simple enzymatic assay for the quantification of C1-specific cellulose oxidation by lytic polysaccharide monooxygenases.

Biotechnology letters·2019
Same author

The influence of comorbid disorders on the episodicity of bipolar disorder in youth.

Acta psychiatrica Scandinavica·2015
Same author

Borderline personality disorder in transition age youth with bipolar disorder.

Acta psychiatrica Scandinavica·2015
Same author

Dyadic discord at baseline is associated with lack of remission in the acute treatment of chronic depression.

Psychological medicine·2009
Same author

Anxiety in middle adulthood: effects of age and time on the 14-year course of panic disorder, social phobia and generalized anxiety disorder.

Psychological medicine·2008
Same author

Do risk factors for suicidal behavior differ by affective disorder polarity?

Psychological medicine·2008
Same journal

Single Ayahuasca administration attenuates alcohol relapse and associated behavioral, neurochemical, and oxidative alterations in rats.

Progress in neuro-psychopharmacology & biological psychiatry·2026
Same journal

Altered dorsal striatal subregional connectivity associated with distinct executive function deficits in first-episode, drug-naïve major depressive disorder: Evidence from functional connectivity and granger causality analysis.

Progress in neuro-psychopharmacology & biological psychiatry·2026
Same journal

Chronic pain and stress: unravelling the common neuroinflammatory, immune and endocrine mechanisms for novel therapeutic approaches.

Progress in neuro-psychopharmacology & biological psychiatry·2026
Same journal

Predicting anhedonia and negative cognitive processing changes after 8-week SSRIs treatment in depression from individual differential structural covariance network.

Progress in neuro-psychopharmacology & biological psychiatry·2026
Same journal

Mapping intrinsic neural timescale alterations in major depressive disorder.

Progress in neuro-psychopharmacology & biological psychiatry·2026
Same journal

Probiotics in reducing negative symptoms of schizophrenia: A systematic review and meta-analysis.

Progress in neuro-psychopharmacology & biological psychiatry·2026
See all related articles

Panic disorder (PD) is a chronic mental health condition affecting many, often accompanied by depression and phobias. Long-term treatment, including therapy and medication, is frequently necessary for managing symptoms and improving patient outcomes.

Area of Science:

  • Psychiatry and Behavioral Science
  • Clinical Psychology

Background:

  • Panic disorder (PD) is a prevalent condition, affecting at least 10% of the population, and has been recognized for over a century.
  • Historically viewed differently, PD was formally classified as a distinct syndrome in the DSM-III in 1987.
  • PD is frequently comorbid with other psychiatric conditions, including depression, phobias, and obsessions, impacting patient severity and prognosis.

Purpose of the Study:

  • To describe the clinical course patterns of panic disorder and related conditions.
  • To examine the long-term outcomes and treatment needs of individuals with panic disorder.

Main Methods:

  • The study utilizes data from the ongoing, multi-site, naturalistic, and longitudinal HARP study.
  • The research involves the examination of patients with current or past diagnoses of panic disorder.

Related Experiment Videos

Main Results:

  • Panic disorder is often a chronic illness, with a significant percentage of patients showing little improvement even after extensive treatment.
  • The duration of PD correlates with the degree of impairment, with longer durations associated with greater impairment.
  • A high comorbidity rate exists between PD and major depression, with patients experiencing both conditions representing a more severely ill group.

Conclusions:

  • Panic disorder is a chronic and often debilitating condition requiring long-term management strategies.
  • A substantial portion of PD patients necessitate ongoing treatment, which may include behavioral therapy and/or pharmacotherapy.
  • Further long-term studies on maintenance treatments for anxiety disorders, including PD, are crucial for effective clinical management.