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[Poisonings and gas accidents]
1Medisinsk klinikk, Ullevål sykehus, Oslo.
Summary
New guidelines recommend less gastric lavage and induced vomiting for acute poisoning. Toxicokinetic data show limited use for haemoperfusion and no use for forced acidic diuresis in poison treatment.
Area of Science:
- Toxicology
- Emergency Medicine
Context:
- Acute poisoning management
- Gas exposure incidents
Purpose:
- Discuss recent trends in acute poisoning treatment
- Incorporate WHO/IPCS guidelines
- Evaluate toxicokinetic efficacy of elimination procedures
Summary:
- Recommends a more restrictive approach to gastric lavage and induction of emesis.
- Highlights limited indications for haemoperfusion based on toxicokinetic evaluation.
- States that forced acidic diuresis is no longer advised for acute poisoning.
Impact:
- Informs clinical practice regarding updated poisoning treatment protocols.
- Promotes evidence-based decision-making in emergency toxicology.
- Reduces the use of potentially ineffective or harmful interventions.