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[Clinical aspects of autoimmune thrombocytopenic purpura]
1Kliniki Hematologii A.M., Lublinie.
Autoimmune thrombocytopenic purpura (ATP) is a relatively common haematological problem. ATP comprises three distinct clinical entities: idiopathic acute thrombocytopenic purpura, idiopathic chronic thrombocytopenic purpura and secondary autoimmune thrombocytopenia which is associated with other autoimmune diseases. In acute ATP the majority of patients recover spontaneously within 3 months. In chronic ATP 75% of patients respond to corticosteroids and splenectomy and need no further therapy. Other forms of treatment have been evaluated for refractory patients. This is a group of particularly high risk and more aggressive forms of treatment, which can be justified, are discussed.
Autoimmune thrombocytopenic purpura (ATP) is a relatively common haematological problem. ATP comprises three distinct clinical entities: idiopathic acute thrombocytopenic purpura, idiopathic chronic thrombocytopenic purpura and secondary autoimmune thrombocytopenia which is associated with other autoimmune diseases. In acute ATP the majority of patients recover spontaneously within 3 months. In chronic ATP 75% of patients respond to corticosteroids and splenectomy and need no further therapy. Other forms of treatment have been evaluated for refractory patients. This is a group of particularly high risk and more aggressive forms of treatment, which can be justified, are discussed.