Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Obesity and the heart

M A Alpert1, M W Hashimi

  • 1Division of Cardiology, University of South Alabama, College of Medicine, Mobile.

The American Journal of the Medical Sciences
|August 1, 1993
PubMed
Summary

Obesity can cause heart problems like obesity cardiomyopathy, leading to heart failure. Weight loss and medication can help manage this condition.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of obesity and weight loss on ventricular repolarization: a systematic review and meta-analysis.

Obesity reviews : an official journal of the International Association for the Study of Obesity·2016
Same author

Short-term fluctuations of plasma NT-proBNP levels in patients with new-onset atrial fibrillation: a way to assess time of onset?

Heart (British Cardiac Society)·2010
Same author

Dyslipidemia in the metabolic syndrome: clinical implications and management.

Minerva cardioangiologica·2006
Same author

Obesity and the electrocardiogram.

Obesity reviews : an official journal of the International Association for the Study of Obesity·2005
Same author

Obesity cardiomyopathy: pathophysiology and evolution of the clinical syndrome.

The American journal of the medical sciences·2001
Same author

Management of obesity cardiomyopathy.

The American journal of the medical sciences·2001

Area of Science:

  • Cardiology
  • Metabolic Disorders
  • Pulmonary Medicine

Background:

  • Obesity can lead to significant cardiac alterations independent of hypertension or other heart diseases.
  • Increased blood volume in obesity creates a high cardiac output state, potentially causing ventricular dilation and hypertrophy.

Purpose of the Study:

  • To describe the cardiac structural and functional changes associated with obesity, termed obesity cardiomyopathy.
  • To discuss the implications of obesity on diastolic and systolic heart function.
  • To highlight associated conditions and treatment strategies.

Main Methods:

  • Review of existing literature on obesity and cardiac function.
  • Analysis of the pathophysiological mechanisms linking obesity to cardiac remodeling.
  • Discussion of clinical manifestations and management.

Main Results:

  • Obesity can cause eccentric left ventricular hypertrophy, leading to diastolic dysfunction.
  • Systolic dysfunction may develop if the left ventricle cannot adapt to increased wall stress.
  • Obesity cardiomyopathy can manifest as congestive heart failure.
  • Sleep apnea/obesity hypoventilation syndrome is a serious comorbidity in morbidly obese individuals.

Conclusions:

  • Obesity cardiomyopathy is a distinct disorder characterized by cardiac structural and functional changes.
  • Management includes weight loss, salt restriction, and diuretics, with potential roles for digitalis and vasodilators.
  • Central obesity and metabolic alterations increase coronary heart disease risk.

Related Experiment Videos