Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Exercise training decreases plasma cholesteryl ester transfer protein

R L Seip¹, P Moulin, T Cocke

¹Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63110-1093.

Arteriosclerosis and Thrombosis : a Journal of Vascular Biology

|September 1, 1993

Summary

Regular exercise significantly reduces cholesterol ester transfer protein (CETP) levels in healthy adults. This reduction may play a role in exercise-induced changes in cholesterol distribution among lipoproteins.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Cardio-Renal Syndrome In Patients Hospitalized In The Cardiology Department Of The University Hospital Center Yalgado OUEDRAOGO (CHUYO): Epidemiology, Clinic, Paraclinic And Course's Aspects].

Le Mali medical·2023

Same author

Complications of sinusitis: An 80-case series from the ENT and neurosurgery departments of the Fann university hospital center of Dakar, Senegal.

European annals of otorhinolaryngology, head and neck diseases·2020

Same author

Evaluation of transfusion practices in sickle cell disease in Senegal: cohort study of 1078 patients with sickle cell disease.

Medecine et sante tropicales·2018

Same author

[Five years assessment of cardiac stimulation in two public hospitals in Burkina Faso: An experiment of collaboration with two hospitals in Auvergne].

Annales de cardiologie et d'angeiologie·2017

Same author

Physiologic and genetic evidence links hemopexin to triglycerides in mice and humans.

International journal of obesity (2005)·2017

Same author

[IgG responses to candidate malaria vaccine antigens in the urban area of Dakar (Senegal): evolution according to age and parasitemia in patients with mild symptoms].

Bulletin de la Societe de pathologie exotique (1990)·2015

Area of Science:

Cardiovascular Health
Exercise Physiology
Lipid Metabolism

Background:

Cholesterol ester transfer protein (CETP) facilitates cholesterol transfer between lipoproteins.
Exercise training is known to alter lipoprotein profiles and lipid metabolism.

Purpose of the Study:

To investigate the impact of endurance exercise on plasma CETP concentrations.
To determine if changes in CETP mediate exercise-associated cholesterol redistribution.

Main Methods:

57 healthy normolipidemic men and women underwent 9-12 months of exercise training.
Plasma CETP levels were measured before and after the training period.
Changes in VO2max, body weight, and lipoprotein parameters were assessed.

Related Experiment Videos

Main Results:

Exercise training significantly increased VO2max and HDL-C, and decreased body weight and triglycerides.
Plasma CETP concentration decreased significantly in both men and women post-training.
The reduction in CETP was observed irrespective of significant weight loss.

Conclusions:

Endurance exercise training effectively lowers plasma CETP levels in healthy individuals.
Reduced CETP may contribute to the favorable alterations in lipoprotein cholesterol observed with exercise.
Exercise-induced changes in CETP warrant further investigation in cardiovascular disease prevention.