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New imaging techniques in gastrointestinal cancer
1Garden State Cancer Center, Center for Molecular Medicine and Immunology, Newark, NJ 07103.
Current Opinion in Oncology
|July 1, 1993
Summary
Recent advances in gastrointestinal tumor imaging, including new biologic agents, improve cancer detection and staging. These innovations enhance accuracy and offer new possibilities for colorectal cancer management.
Area of Science:
- Oncology
- Medical Imaging
Background:
- Gastrointestinal tumor imaging has seen significant advancements.
- Conventional and functional imaging methods are increasingly combined for improved accuracy.
Purpose of the Study:
- To review recent progress in anatomic and functional imaging of gastrointestinal tumors.
- To highlight the impact of new biologic imaging agents in oncology.
Main Methods:
- Review of recent studies on gastrointestinal tumor imaging modalities.
- Focus on positron-emission tomography, receptor scintigraphy, and radioimmunodetection.
- Discussion of the first FDA-approved antibody-based cancer imaging agent.
Main Results:
- Combination of imaging modalities enhances diagnostic accuracy.
- New functional tests improve detection of local versus extended cancer sites.
- Antibody-based agents show promise for improved staging and detecting occult colorectal cancer.
Conclusions:
- Advances in imaging, particularly biologic agents, are transforming gastrointestinal tumor management.
- These agents offer improved staging and detection of occult disease, especially in colorectal cancer.
- Radioactive biologic targeting agents hold potential for positron-emission tomography and radioimmunotherapy.