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Comparative bioavailability study of acetaminophen solutions used in hospital formulary
S Prakongpan1, R Puncoke, T Nagai
1Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Biological & Pharmaceutical Bulletin
|June 1, 1993
Abstract:
To learn the influence of polyethylene glycol (PEG) on bioavailability, this study compared the bioavailability of acetaminophen in the presence of 10% ethanol (acetaminophen-ethanol liquid) to that in the presence of 10% PEG (acetaminophen-PEG liquid) since these two preparations are commonly used in hospital formulary. The results in Thai male volunteers showed there was not significantly different.