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Updated: Aug 17, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Bullous dermatoses associated with systemic disease
1Department of Dermatology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
Abstract:
The bullous diseases that are neither immune-mediated nor inherited form a heterogeneous group that may be classified according to their major histopathologic characteristics. Such a classification allows clear distinctions to be made between entities that may have clinical similarities such as staphylococcal scalded skin syndrome, toxic shock syndrome, erythema multiforme/toxic epidermal necrolysis, and acute graft-versus-host disease. Proper differentiation of these entities is critical for their study and for appropriate management.
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