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Clinical research: any future?

J Genest1

  • 1Clinical Research Institute of Montreal, Quebec.

Clinical and Investigative Medicine. Medecine Clinique Et Experimentale
|June 1, 1993
PubMed
Summary
This summary is machine-generated.

Canadian laboratory-based clinical research faces a crisis due to funding and a shift towards molecular biology. Reinvigoration requires increased funding for fellowships and enhanced collaboration between scientists.

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Area of Science:

  • Clinical Research
  • Medical Education
  • Biomedical Science Policy

Background:

  • Laboratory-based clinical research in Canada is experiencing a significant crisis.
  • Contributing factors include inadequate financial support for research fellows and a trend towards molecular/cellular approaches over traditional pathophysiology.

Purpose of the Study:

  • To identify the key challenges facing laboratory-based clinical research in Canada.
  • To propose actionable solutions for its revitalization and ensure the effective translation of basic science advances to clinical practice.

Main Methods:

  • Analysis of current trends in research funding and training.
  • Examination of the impact of molecular biology's dominance on clinical research and patient care.
  • Review of successful collaborative models in clinical research.

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Main Results:

  • Inadequate remuneration for research fellows pursuing international training.
  • Overemphasis on molecular biology and genetics, creating a disconnect with clinical medicine.
  • Limited time for patient care due to intensive molecular research.

Conclusions:

  • Reinvigorating laboratory-based clinical research is crucial for translating basic science to clinical care.
  • Recommendations include increased fellowship funding ($50-60,000), fostering collaboration between PhD and clinical scientists, and allocating more research funds to support this vital area and train clinical scientists.