Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primary bladder pheochromocytoma without hypertension

Y Suzuki1, T Nakada, H Suzuki

  • 1Department of Urology, Yamagata University, School of Medicine, Japan.

International Urology and Nephrology
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Purification and characterization of DNA topoisomerase IV in Escherichia coli.

The Journal of biological chemistry·1992
Same author

Identification of inducible calmodulin-dependent nitric oxide synthase in the liver of rats.

The Journal of biological chemistry·1992
Same author

Inhibition of cell attachment, invasion and metastasis of human carcinoma cells by anti-integrin beta 1 subunit antibody.

Japanese journal of cancer research : Gann·1992
Same author

Enzymatic inactivation of tachykinin neurotransmitters in the isolated spinal cord of the newborn rat.

Neuroscience research·1992
Same author

Alpha-fetoprotein-producing immature mediastinal teratoma showing rapid and massive recurrent growth in an adult.

Acta pathologica japonica·1992
Same author

Ki-67 antibody labeling index in colorectal carcinoma.

Journal of clinical gastroenterology·1992

This case study discusses a rare urinary bladder pheochromocytoma. Despite high urinary norepinephrine, the patient maintained normal blood pressure and experienced no fluctuations during urination.

Area of Science:

  • Urology
  • Endocrinology
  • Oncology

Background:

  • Pheochromocytomas are rare neuroendocrine tumors typically arising in the adrenal medulla.
  • Urinary bladder pheochromocytomas are exceptionally rare, accounting for a small fraction of all pheochromocytoma cases.
  • These tumors can secrete catecholamines, leading to hypertension and other symptoms.

Observation:

  • A patient presented with a confirmed case of urinary bladder pheochromocytoma.
  • Elevated urinary norepinephrine levels were detected.
  • The patient remained normotensive and did not exhibit blood pressure fluctuations during or after micturition.

Findings:

  • The case highlights a discrepancy between high urinary catecholamine levels and the absence of classic hypertensive symptoms in a patient with bladder pheochromocytoma.

Related Experiment Videos

  • This suggests that urinary bladder pheochromocytomas may present atypically, without significant hemodynamic compromise.
  • Normotension in the presence of elevated urinary norepinephrine warrants further investigation into the tumor's specific secretory profile or potential counter-regulatory mechanisms.

    • Implications:

    • This atypical presentation broadens the clinical spectrum of pheochromocytoma, particularly for rare variants like those in the urinary bladder.
    • It emphasizes the importance of considering pheochromocytoma in patients with unexplained elevated urinary catecholamines, even in the absence of hypertension.
    • Further research is needed to understand the pathophysiology behind normotensive pheochromocytomas and their management strategies.