Related Experiment Videos
Induction of alloxan/streptozotocin diabetes in dogs: a revised experimental technique
H R Anderson1, A W Stitt, T A Gardiner
1Department of Ophthalmology, Queen's University of Belfast, UK.
Laboratory Animals
|July 1, 1993
Abstract:
The diabetic dog represents an excellent model for use in many aspects of diabetic research. The present paper describes, in detail, a reproducible experimental protocol for the successful induction of chemical diabetes in beagles using a combination of the 2 pancreatic beta-cell cytoxic agents alloxan and streptozotocin.