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Circulatory reflexes in myocardial infarction

B J Kirby

    British Heart Journal
    |February 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    The Valsalva manoeuvre revealed impaired vasoconstriction in most acute myocardial infarction patients, suggesting reflex inhibition may explain circulatory issues and patient deterioration.

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    Area of Science:

    • Cardiology
    • Physiology

    Background:

    • Acute myocardial infarction (AMI) can affect circulatory reflexes.
    • Understanding these reflexes is crucial for patient management and transport.

    Purpose of the Study:

    • To investigate circulatory reflex responses to the Valsalva manoeuvre in patients with AMI.
    • To identify potential mechanisms behind abnormal vasoconstriction in AMI.

    Main Methods:

    • The Valsalva manoeuvre was performed on 22 patients with acute myocardial infarction.
    • Circulatory responses, including pulse pressure and diastolic pressure, were monitored.

    Main Results:

    • Four patients exhibited a 'square wave' response indicative of cardiac failure.
    • Eighteen patients showed a significant fall in pulse pressure without a compensatory rise in diastolic pressure, suggesting impaired vasoconstriction.

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  • This impairment was not attributable to acidosis, hypocapnia, or hypoxemia.

    • Conclusions:

    • Impaired vasoconstriction in AMI patients may be due to reflex inhibition.
    • Abnormal Valsalva responses have implications for patient transport and may contribute to rapid deterioration in arrhythmias.