Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Isocyanate induced lung disease

¹VA Lakeside Medical Center, Chicago, Illinois.

Agents and Actions. Supplements

|January 1, 1993

Summary

This summary is machine-generated.

Isocyanate exposure can cause lung disease through immune system responses. This review focuses on the immunologic mechanisms driving isocyanate-induced lung disease pathogenesis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Human leucocyte antigens (HLA) and trimellitic anhydride (TMA) immunological lung disease.

Respiratory medicine·2000

Same author

Corticosteroid therapy in an additional 13 cases of Stevens-Johnson syndrome: a total series of 67 cases.

Allergy and asthma proceedings·2000

Same author

Review of trimellitic anhydride (TMA) induced respiratory response.

Allergy and asthma proceedings·1997

Same author

Bean bag allergy revisited: a case of allergy to inhaled soybean dust.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·1996

Same author

Induction of type I hypersensitivity in guinea pigs after inhalation of phthalic anhydride.

The Journal of allergy and clinical immunology·1994

Same author

Evolution of patient care, education, and research in asthma by one academic team of investigators over 35 years: the Northwestern University Medical School Division of Allergy-Immunology experience (Part Two).

Allergy proceedings : the official journal of regional and state allergy societies·1994

Area of Science:

Immunology
Pulmonology
Toxicology

Background:

Isocyanates are reactive chemicals widely used in industry.
Occupational exposure to isocyanates can lead to respiratory diseases.
Isocyanate-induced lung disease (IILD) is a significant occupational health concern.

Purpose of the Study:

To review the pathogenesis of isocyanate-induced lung disease.
To emphasize the role of immunologic mechanisms in IILD.

Main Methods:

Literature review of existing studies on isocyanate exposure and lung disease.
Analysis of immunologic pathways involved in IILD.
Synthesis of current understanding of disease mechanisms.

Main Results:

Related Experiment Videos

IILD pathogenesis involves complex immune responses.
Sensitization and subsequent allergic reactions are key.
Cellular and humoral immunity contribute to lung damage.

Conclusions:

Immunologic mechanisms are central to the development of isocyanate-induced lung disease.
Understanding these mechanisms is crucial for prevention and treatment.
Further research into specific immune pathways may yield targeted therapies.