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(+/-) isoprenaline revisited: adverse effects of sympathomimetics in asthma
T T Hansel1, F Schwarz, B Villiger
1Swiss Institute of Allergy and Asthma Research (SIAF), Sandoz Pharma Ltd., Basel.
Agents and Actions. Supplements
|January 1, 1993
Abstract:
It is a matter of concern that regular, excessive use of contemporary sympathomimetics has been associated with morbidity and mortality from asthma. As a consequence, restrictions on sympathomimetic usage have recently been advocated in asthma management guidelines. he association between excessive use of inhaled (+/-)isoprenaline and an epidemic of asthma deaths in the 1960s provides a precedent; hence, we have reviewed the numerous clinical and experimental reports concerning (+/-) isoprenaline to provide insight into the present controversy.