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Investigation of a biodegradable, implantable antibiotic delivery system on rate of wound infection
M T Sasmor1, W D Morain, L M Balestrero
1Section of Plastic and Reconstructive Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756.
Annals of Plastic Surgery
|June 1, 1993
Abstract:
Biodel, a bioabsorbable polymer, may be adapted to serve as an antibiotic delivery system for high local concentrations of drugs. In an autocontaminated, irradiated wound model with a high intrinsic infection rate, implanted gentamicin-impregnated Biodel beads prevented wound infections in the submental area of rats.