[Prevention of myopathies and cardiomyopathies in swine using magnesium aspartate hydrochloride]

The efficiency of magnesium-aspartate-hydrochloride (MAH) in prophylaxis of porcine stress-induced myopathy was investigated. For the examination a conveyor belt was used. MAH was administered orally or intramuscularly. Clinical investigations, blood specimen collections and ECG were carried out before and after running. Stress-induced tachypnoea and tachycardia and hyperthermia were reduced after both forms of administration of MAH. The enzyme activity of CK, LDH and alpha-HBDH increased slighter after oral and i. m. application. The increase of serum glucose concentration as well as serum lactate level were reduced after oral and i. m. substitution with MAH. In the ECG apart from the relative diastolic period all time values were significantly prolonged after MAH-substitution. The results indicate that several stress-induced changes of clinical and metabolic parameters can be reduced by administration of MAH.