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Cerebrospinal fluid thyrotropin-releasing hormone concentrations in patients with anxiety disorders
M D Fossey1, R B Lydiard, J C Ballenger
1Institute of Psychiatry, Medical University of South Carolina, Charleston 29425.
The Journal of Neuropsychiatry and Clinical Neurosciences
|January 1, 1993
Abstract:
In a study of 45 patients with anxiety disorders and 11 control subjects, mean cerebrospinal fluid (CSF) concentrations of thyrotropin-releasing hormone (TRH) were not significantly different between nonpsychiatric control subjects and those with panic disorder, generalized anxiety disorder, or obsessive-compulsive disorder. Male subjects, regardless of diagnosis, had significantly higher mean CSF concentrations of TRH than females.