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Cystitis cystica: characteristics of the disease in children
Insights
Cystitis cystica, a bladder condition, frequently affects girls and is linked to urinary tract infections and anomalies. This condition may cause reflux and bladder outlet obstruction in children.
Area of Science:
- Pediatric Urology
- Pediatric Pathology
- Pediatric Infectious Diseases
Background:
- Cystitis cystica is a condition characterized by cyst formation in the bladder wall.
- Its occurrence and implications in pediatric populations require further elucidation.
Purpose of the Study:
- To investigate the prevalence and clinical characteristics of cystitis cystica in children.
- To identify associated urinary tract infections and anomalies.
Main Methods:
- Cystoscopy was performed on 157 children aged 9 1/2 months to 14 years.
- Urinalysis and imaging were conducted to assess for infections and anomalies.
- Histological examination of cyst tissue was performed.
Main Results:
- Cystitis cystica was diagnosed in 157 children, predominantly girls (153 vs. 4 boys).
- Urinary tract infections, commonly E. coli, were nearly universal.
- Vesico-ureteric reflux and other urinary tract anomalies were frequently observed.
Conclusions:
- Cystitis cystica in children is strongly associated with urinary tract infections and anomalies.
- The condition may predispose to vesico-ureteric reflux and bladder outlet obstruction.
- Early diagnosis and management are crucial for pediatric patients.
Abstract:
Cystitis cystica was found at cystoscopy in 157 children between the ages of 9 1/2 months and 14 years. Girls were affected much more often than boys, the proportion being 153 to 4. Urinary infection, most commonly caused by E. coli, was almost invariable. Urinary tract anomalies, in particular vesico-ureteric reflux, were frequently present. Histologically, the cysts were composed of submucous aggregations of lymphoid tissue. Cystitis cystica affecting the ureteric orifices may contribute to the occurence of reflux and involvement of the bladder neck may produce some degree of vesical outlet obstruction.
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