[Antibiotic therapy in pregnancy]

Antibiotics are the most frequently prescribed medications in pregnancy, their application and choice should be made according to the highest criteria. Penicillins and cephalosporins can be safely used in pregnancy, however, their side effects such as allergic reactions present a greater therapeutic problem. Tetracyclines, chloramphenicol and quinolones are strictly contraindicated in pregnancy. 5-nitroimidazole derivatives, aminoglycosides and sulfonamides are indicated only in severe infections. Not only the risk of malformation is increased in the embryonic stage, i.e. in the first 8 weeks of gestation, but also at the time of delivery with the use of drugs as sulfonamides, which can cause icterus.