Coxiella burnetii serology in granulomatous hepatitis

Granulomatous hepatitis as the sole manifestation of acute Q fever has been reported only rarely, although minimal hepatic dysfunction may be common in the acute disease. In this paper we report two patients with acute Q fever who presented with hepatitis; one of whom had granulomatous hepatitis on liver biopsy. We discuss the serological diagnosis of acute and chronic Q fever particularly in relation to hepatitis.