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Association between Raynaud's phenomenon and migraine in a random population of hospital employees
S T O'Keeffe1, N P Tsapatsaris, W P Beetham
1Section of Vascular Medicine and Hypertension, Lahey Clinic Medical Center, Burlington, MA 01085.
Objective:
To determine the relationship between migraine and Raynaud's phenomenon.
Methods:
A detailed headache questionnaire was completed by 41 subjects with Raynaud's phenomenon identified in a random survey of hospital employees and by a group matched for age and sex without Raynaud's phenomenon.
Results:
The prevalence of migraine was increased significantly in the group with Raynaud's phenomenon compared with the control group (24/41, 58.5% vs 10/41, 24.4%; p = 0.002). This result agrees with findings in hospital-based studies of patients with Raynaud's phenomenon.
Conclusion:
The prevalence of migraine is significantly increased in subjects with Raynaud's phenomenon, suggesting that these conditions may share a common pathogenetic defect or mechanism.