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Published on: April 3, 2016
Excimer photorefractive keratectomy for myopia
L W Piebenga1, C S Matta, M R Deitz
1University of Missouri-Kansas City School of Medicine, Department of Ophthalmology, Eye Foundation of Kansas City, MO 64108.
Ophthalmology
|September 1, 1993
Summary
Photorefractive keratectomy (PRK) using an excimer laser is safe and effective for myopia reduction. Results are predictable and stable after six months, showing promise for refractive surgery.
Area of Science:
- Ophthalmology
- Laser Surgery
Background:
- Excimer laser photorefractive keratectomy (PRK) is a refractive surgery technique.
- Evaluating the safety, effectiveness, predictability, and stability of PRK is crucial for its clinical application.
Purpose of the Study:
- To assess the safety, effectiveness, predictability, and stability of excimer laser PRK.
- To evaluate the impact of nitrogen purge and postoperative steroids on PRK outcomes.
Main Methods:
- 133 normally sighted eyes underwent excimer laser PRK.
- A 5.0 mm ablation zone, 160 mJ/cm2 fluence, and 5 Hz frequency were used.
- Nitrogen purge and steroid effects were analyzed.
Main Results:
- No significant complications were observed.
- Refraction stabilized after initial over-correction, with 6-month results predicting long-term outcomes (P < 0.0001).
- Significant visual acuity improvement was noted without nitrogen purge; steroid treatment showed no significant benefit.
Conclusions:
- PRK is a safe and effective procedure for myopia reduction.
- Outcomes are predictable and stable approximately six months post-surgery.
- PRK holds significant promise as a refractive surgery option with ongoing refinements.

