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[Diclofenac does not change the characteristics of anesthetic induction with midazolam]
E Carrero1, J Castillo, A Bogdanovich
1Departamento de Anestesiología y Reanimación, Hospital Clínic i Provincial, Barcelona.
Revista Espanola De Anestesiologia Y Reanimacion
|July 1, 1993
Abstract:
To examine the possible interaction between diclofenac and midazolam, 20 patients undergoing orthopedic or traumatologic surgery were studied. All were anesthetized with 0.3 mg/kg intravenous midazolam after having been premedicated randomly with either placebo (control group, n = 10) or with 1 mg/kg intravenous diclofenac (n = 10). Anesthetic characteristics (rate of induction and depth) were similar in both groups, indicating that no clinical interaction between the two drugs can be identified.