Transtympanic electrocochleography in Menière's disease using clicks and tone-bursts

Transtympanic electrocochleography (ECoG), using clicks and tone-bursts at 500, 1000, and 2000 Hz, was employed to study 80 patients with Meniere's disease and 25 non-Meniere's patients. The magnitude of the negative summating potential and the summating potential:action potential ratio (SP:AP) were examined in both groups. Groups were further divided based upon degree of hearing loss and audiometric configuration. An elevated SP:AP ratio was found in 83.7 percent of the Meniere's ears and 12 percent of the non-Meniere's. The likelihood of obtaining a positive ECoG in Meniere's patients was strongly related to degree of hearing loss but not audiometric configuration.