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Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell
Biochimica Et Biophysica Acta
|September 23, 1993
Abstract:
A cDNA clone encoding bone morphogenetic protein 4 (BMP 4) has been isolated from a primary fetal rat calvarial cell cDNA library. Sequencing of this clone has revealed a single open reading frame encoding a 408 amino acid protein. Comparison of 5' noncoding exon 1 portion of this cDNA with that of human bone and prostate BMP4 cDNA shows that BMP4 gene expression may possess tissue specificity.