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[Computed tomography in a case of pseudomembranous colitis]
Abstract:
Pseudomembranous colitis (PMC) is an infectious colitis usually occurring as a complication of antibiotic therapy. The computed tomography (CT) findings of 10 patients with PMC are reviewed. All patients demonstrated an abnormal large bowel wall with an average thickness of 13 mm (range 7-31 mm). Additional, but less frequent findings included mesenteric inflammation, ascites, pleural effusions, and dilatation of the large or small bowel. Pancolonic involvement was seen in 7 cases, while three patients had focal colitis. Although the CT appearance of PMC is not specific, the diagnosis may be suggested in the proper clinical setting.
Insights
Computed tomography (CT) can help diagnose pseudomembranous colitis (PMC), an antibiotic-associated condition. Review of 10 patients revealed characteristic large bowel wall thickening on CT scans.
Area of Science:
- Gastroenterology
- Radiology
- Infectious Diseases
Background:
- Pseudomembranous colitis (PMC) is an infectious colitis often linked to antibiotic use.
- Accurate diagnostic methods are crucial for timely treatment.
Purpose of the Study:
- To review and characterize the computed tomography (CT) findings in patients diagnosed with pseudomembranous colitis (PMC).
- To assess the utility of CT in suggesting the diagnosis of PMC in a clinical context.
Main Methods:
- Retrospective review of CT scans from 10 patients with confirmed PMC.
- Analysis of large bowel wall thickness and other abdominal/pelvic findings.
Main Results:
- All 10 patients exhibited abnormal large bowel wall thickening, averaging 13 mm (range 7-31 mm).
- Mesenteric inflammation, ascites, pleural effusions, and bowel dilatation were less common findings.
- Pancolonic involvement occurred in 7 cases; focal colitis was present in 3.
Conclusions:
- While CT findings for PMC are not entirely specific, they can strongly suggest the diagnosis.
- CT is a valuable imaging modality for evaluating patients with suspected pseudomembranous colitis, especially in the appropriate clinical setting.