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[The effect of fluctuating currents on the time course of apomorphine-induced stereotypy in rats]
Biulleten' Eksperimental'Noi Biologii I Meditsiny
|June 1, 1993
Abstract:
The external rhythmogenic influence (repeated fluctuation low intensity) disorganized the time-course and attenuated the apomorphine-induced stereotyped behavior in rats. A decrease in the number of 4-9-minute waves on chronograms in comparison with control an animals indicated reduction of stability of the pharmacological response and the rapid formation of tolerance to the drug.