Skin manifestations of immune disorders in children

During the past decade, there has been enormous progress in the field of immunology, including identification of the molecular basis of many types of immunodeficiency. Many of these defective immunologic responses are associated with a range of cutaneous manifestations. Other clinically recognized skin diseases are now suspected to result from exaggerated immune responses. This paper summarizes some of the most recent clinically relevant information on pathogenesis, classification, diagnosis, and treatment within this group of disorders.