Related Experiment Video
Updated: Jun 25, 2026

11:08
Recording Temperature-induced Neuronal Activity through Monitoring Calcium Changes in the Olfactory Bulb of Xenopus laevis
Published on: June 3, 2016
Calcium-binding proteins in the inner ear of Xenopus laevis (Daudin)
1University of Salzburg, Department of Physiology, Austria.
Brain Research
|July 16, 1993
Abstract:
Parvalbumin, S-100, calbindin-D28K and calmodulin-immunoreactive sensory hair cells were located in the inner ear of tadpoles and mature frogs of Xenopus laevis (Daudin). The relative number of immunoreactive cells varied in different compartments of the inner ear, depending on the Ca-binding protein studied.
Related Concept Videos
Hair Cells
Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.
Calmodulin-dependent Signaling
Calmodulin (CaM) is a calcium-binding protein in eukaryotes that controls various calcium-regulated cellular processes. It has four calcium-binding sites that bind calcium to form the calcium-calmodulin ( Ca2+-CaM) complex. GPCR stimulation increases the calcium levels in the cells that bind to CaM and induces a conformational change.
The Ca2+-CaM complex does not have enzymatic activity by itself. Instead, the complex binds downstream target proteins, including membrane proteins or enzymes,...
The Ca2+-CaM complex does not have enzymatic activity by itself. Instead, the complex binds downstream target proteins, including membrane proteins or enzymes,...

