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Trisomy 4 with double minute chromosomes in acute nonlymphocytic leukemia
P W Thompson1, J A Whittaker, H Brennan
1Institute of Medical Genetics, University of Wales College of Medicine, Cardiff, United Kingdom.
Cancer Genetics and Cytogenetics
|August 1, 1993
Abstract:
We report on three further cases of trisomy 4 in acute nonlymphocytic leukemia. In one case the trisomy 4 was accompanied by double minute (dmin) chromosomes. Of the 34 reports of trisomy 4, dmin were also found in five cases, showing a clear nonrandom association between the two cytogenetic abnormalities.