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Lack of 5' BCL2 rearrangements in B-cell leukemia
1Cytogenetic and Molecular Oncology Unit, Christchurch Hospital, New Zealand.
Cancer Genetics and Cytogenetics
|August 1, 1993
Abstract:
We found no rearrangements in the 5' region of the BCL2 gene in DNA samples from 60 patients with chronic B-cell leukemia (CLL). This compares with the presence of these rearrangements in up to 10% of patients in other reports, and suggests that the incidence of 5' BCL2 rearrangements in CLL is considerably less than 10%.