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Hemi-field pattern reversal visual evoked potentials in migraine
S Tsounis1, J Milonas, F Gilliam
1Department of Clinical Neurophysiology, Mental Hospital Thessaloniki, Greece.
Cephalalgia : an International Journal of Headache
|August 1, 1993
Summary
Migraine patients, with or without aura, show normal visual evoked potentials. However, a subgroup with consistently unilateral headaches exhibited shorter P100 latency on the affected side, suggesting altered sensory processing.
Area of Science:
- Neuroscience
- Ophthalmology
- Clinical Neurology
Background:
- Migraine is a common neurological disorder.
- Visual evoked potentials (VEPs) are used to assess visual pathway function.
- Hemi-field pattern reversal VEPs can detect subtle visual pathway abnormalities.
Purpose of the Study:
- To investigate VEP abnormalities in migraine patients.
- To compare patients with migraine with aura and without aura.
- To assess VEPs in relation to headache lateralization.
Main Methods:
- Hemi-field pattern reversal visual evoked potentials (VEPs) were recorded.
- 44 migraine patients (22 with aura, 22 without aura) and 20 controls were studied.
- P100 latency was analyzed between groups and affected/non-affected sides.
Main Results:
- No significant P100 latency differences were found between migraine groups and controls.
- No differences were observed between affected and non-affected sides in most patients.
- A subgroup (14 patients) with constantly unilateral headaches showed significantly shorter P100 latency on the affected side.
Conclusions:
- Migraine with and without aura share common pathogenetic mechanisms.
- The affected retrochiasmatic optic radiation may exhibit increased response to sensory input modulation.
- Unilateral headache patterns in migraine may correlate with specific VEP alterations.