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Related Experiment Videos

Renal ablation with absolute ethanol for nonfunctioning hydronephrosis

Y Hirao1, E Okajima, K Yoshida

  • 1Department of Urology, Nara Medical University, Japan.

European Urology
|January 1, 1993
PubMed
Summary
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Renal ablation using absolute ethanol offers a safe, less invasive alternative to nephrectomy for nonfunctioning hydronephrosis. This minimally invasive procedure effectively shrinks kidneys without major adverse effects, improving patient quality of life.

Area of Science:

  • Urology
  • Interventional Radiology

Background:

  • Nonfunctioning hydronephrosis often necessitates surgical nephrectomy.
  • Existing treatments may involve significant invasiveness and morbidity.

Purpose of the Study:

  • To evaluate the safety and efficacy of renal ablation with absolute ethanol for nonfunctioning hydronephrosis.
  • To assess renal shrinkage and adverse effects following the procedure.

Main Methods:

  • A 3-session protocol was used: percutaneous nephrostomy, transarterial embolization of the renal artery with absolute ethanol, and sclerotherapy of the renal pelvis/ureter.
  • Absolute ethanol was the primary ablative agent in all sessions.

Main Results:

  • All six adult patients demonstrated marked renal shrinkage post-procedure.

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  • No major adverse effects were observed during the follow-up period.
  • The procedure was well-tolerated, indicating a favorable safety profile.

    • Conclusions:

    • Renal ablation with absolute ethanol is a safe and effective alternative to surgical nephrectomy for nonfunctioning hydronephrosis.
    • This minimally invasive approach can preserve patient quality of life by avoiding radical surgery.