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Spectrophotometric analysis of a pharmaceutical preparation by principal component regression
M Blanco1, J Coello, F González
1Departament de Química, Universitat Autònoma de Barcelona, Spain.
Journal of Pharmaceutical Sciences
|August 1, 1993
Abstract:
The use of a principal component regression procedure for quantitative analytical control of pharmaceutical preparations was investigated. The procedure was applied to the simultaneous quantitation of the active compound and preservative of a syrup by resolving their respective UV spectra. The most suitable conditions for quantitation were established and the results were compared with those obtained by HPLC.