Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Calcitonin-testosterone interrelationship. A classic feedback system?

¹Department of Internal Medicine, Ijsselland Hospital, Capelle a.d. Ijssel, Netherlands.

The Netherlands Journal of Medicine

|June 1, 1993

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Genetic architecture of oral glucose-stimulated insulin release provides biological insights into type 2 diabetes aetiology.

Nature metabolism·2024

Same author

MicroRNA 29 modulates β-cell mitochondrial metabolism and insulin secretion via underlying miR-29-OXPHOS complex pathways.

Acta physiologica (Oxford, England)·2024

Same author

Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry·2021

Same author

Mitochondrial clearance of calcium facilitated by MICU2 controls insulin secretion.

Molecular metabolism·2021

Same author

[Guideline 'Organ donation following euthanasia"].

Nederlands tijdschrift voor geneeskunde·2017

Same author

Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes.

Nature communications·2017

Same journal

A diagnostic tool for self-poisoned patients: Analysis of gastric content and lavage fluids.

The Netherlands journal of medicine·2020

Same journal

Answer to Photoquiz A bone disorder with skin lesions.

The Netherlands journal of medicine·2020

Same journal

A bone disorder with skin lesions.

The Netherlands journal of medicine·2020

Same journal

Answer to Photoquiz A fascinating liver abscess.

The Netherlands journal of medicine·2020

Same journal

A fascinating liver abscess.

The Netherlands journal of medicine·2020

Same journal

Answer to Photoquiz A polyposis syndrome.

The Netherlands journal of medicine·2020

See all related articles

Pharmacological doses of calcitonin lower testosterone, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) levels. This suggests calcitonin and testosterone may form a negative feedback system, impacting reproductive hormones.

Area of Science:

Endocrinology
Neuroendocrinology

Background:

Calcitonin is a hormone involved in calcium regulation.
Testosterone influences various bodily functions, including hormone regulation.

Purpose of the Study:

To investigate the effect of calcitonin on serum testosterone, LH, and FSH levels.
To explore the potential feedback relationship between calcitonin and testosterone.

Main Methods:

Calcitonin was administered in pharmacological doses.
Serum concentrations of testosterone, LH, and FSH were measured.

Main Results:

Calcitonin infusion significantly reduced serum testosterone, LH, and FSH.
The effect is hypothesized to occur at the hypothalamic level.

Related Experiment Videos

Conclusions:

Calcitonin may act as a negative feedback regulator in the testosterone hormonal system.
A potential classic negative feedback loop exists between calcitonin and testosterone.