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Updated: Aug 15, 2026
Collection, Isolation, and Flow Cytometric Analysis of Human Endocervical Samples
Published on: July 6, 2014
Comparison of the Cytobrush plus plastic spatula with the Cervex Brush for obtaining endocervical cells
1Department of Obstetrics and Gynecology, St. John's Mercy Medical Center, St. Louis, Missouri.
Objective:
To compare the effectiveness of the Cytobrush plus plastic spatula with that of the Cervex Brush for obtaining acceptable yields of endocervical cells in Papanicolaou smears.
Methods:
We collected 309 smears over a 6-month period, 132 with the Cytobrush plus spatula and 177 with the Cervex Brush. About one-third of the patients in each group were pregnant. Numbers of endocervical cells in the smears were described as none, few, moderate, or many.
Results:
Moderate or large numbers of endocervical cells were collected from 60.5% of the women in the Cervex Brush group and 65.2% of those in the Cytobrush-spatula group. The percentages were not statistically different.
Conclusion:
The Cytobrush plus spatula and the Cervex Brush sampling methods were equally effective in obtaining endocervical cells in routine Papanicolaou smears.
