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Multiple genes for G protein-coupled receptors and their expression in lingual epithelia
K Abe1, Y Kusakabe, K Tanemura
1Department of Agricultural Chemistry, Faculty of Agriculture, University of Tokyo, Japan.
FEBS Letters
|February 1, 1993
Abstract:
Using the polymerase chain reaction (PCR), we identified a gene family including more than 60 members which encoded similar G protein-coupled seven-transmembrane receptors. Sequence analyses of six representatives out of the 60 PCR clones showed that they had significant structural similarity to olfactory and optic receptors. Their expression is restricted in the surface of lingual epithelia.