Meconium ileus equivalent complicating cystic fibrosis in postneonatal children and young adults. Report of 12 cases
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Summary
This summary is machine-generated.Meconium ileus equivalent, a complication of cystic fibrosis, presents with abdominal pain and obstruction. A Gastrografin enema can diagnose and treat this condition in children and young adults.
Area Of Science
- Pediatric Gastroenterology
- Pulmonology
- Medical Imaging
Background
- Meconium ileus equivalent (MIE) is a significant complication in postneonatal cystic fibrosis (CF) patients.
- It presents a diagnostic challenge, often mimicking other abdominal conditions.
Purpose Of The Study
- To describe the clinical presentation and diagnostic approach to MIE in CF patients.
- To evaluate the efficacy of meglumine diatrizoate enemas in diagnosing and treating MIE.
Main Methods
- Retrospective review of twelve postneonatal CF patients diagnosed with MIE between 1950 and 1975.
- Clinical data analysis focusing on symptoms, physical examination findings, and diagnostic imaging.
Main Results
- A characteristic triad of recurrent colicky abdominal pain, right lower quadrant mass, and intestinal obstruction suggests MIE in CF.
- Meglumine diatrizoate (Gastrografin) enema confirmed the diagnosis and served as effective treatment in uncomplicated cases.
Conclusions
- MIE is a critical consideration in postneonatal CF patients presenting with obstructive symptoms.
- Gastrografin enema is a valuable tool for both diagnosing and managing uncomplicated MIE, reducing the need for surgical intervention.