Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Phyllodes tumors

M D Rowell1, R R Perry, J G Hsiu

  • 1Department of Surgery, Eastern Virginia Medical School, Norfolk 23507.

American Journal of Surgery
|March 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interleukin (IL)-1, IL-6, and IL-8 predict mucosal toxicity of vaginal microbicidal contraceptives.

Biology of reproduction·2004
Same author

Multicenter trial of sentinel node biopsy for breast cancer using both technetium sulfur colloid and isosulfan blue dye.

Annals of surgery·2001
Same author

Preclinical experience with two selective progesterone receptor modulators on breast and endometrium.

Steroids·2000
Same author

Multiple ectopic parathyroid glands.

The American surgeon·2000
Same author

A phase III trial of ifosfamide with or without cisplatin in carcinosarcoma of the uterus: A Gynecologic Oncology Group Study.

Gynecologic oncology·2000
Same author

Parameters that predict nipple involvement in breast cancer.

Journal of the American College of Surgeons·2000
Same journal

Innovative management of Anterior Cutaneous Nerve Entrapment Syndrome (ACNES): A meta-analysis and introduction of a new robotic approach with patient-based algorithm.

American journal of surgery·2026
Same journal

Does the risk outweigh the benefit? Clot progression, recanalization & complications of anticoagulation therapy in acute pancreatitis with concomitant splanchnic vein thrombosis.

American journal of surgery·2026
Same journal

High and low body mass index and 90-day postoperative outcomes in patients with Crohn's disease undergoing abdominal surgery.

American journal of surgery·2026
Same journal

Women with firearm injuries: A multicenter mixed-methods study.

American journal of surgery·2026
Same journal

SBAS presidential address: A surgeon-scientist's journey from haptic science to digital performance metrics.

American journal of surgery·2026
Same journal

Using Dr. Google and AI to stay informed.

American journal of surgery·2026
See all related articles

Phyllodes tumors of the breast, though rare, can recur even if low-grade. Inadequate excision of these breast lesions increases recurrence risk, highlighting the importance of surgical extent for patient outcomes.

Area of Science:

  • Oncology
  • Pathology
  • Surgical Oncology

Background:

  • Phyllodes tumors are rare breast lesions with unpredictable clinical behavior.
  • Accurate prediction of phyllodes tumor behavior and recurrence risk remains challenging.

Purpose of the Study:

  • To investigate the correlation between clinicopathologic features and clinical outcomes in phyllodes tumors.
  • To assess the impact of surgical intervention extent on recurrence rates and patient survival.

Main Methods:

  • Retrospective review of 18 patients diagnosed with phyllodes tumors.
  • Analysis of pathologic characteristics, including tumor grade and cellular features.
  • Evaluation of clinical behavior, recurrence patterns, and treatment outcomes following surgical excision.

Related Experiment Videos

Main Results:

  • Three recurrences were observed within a median follow-up of 26 months.
  • Recurrence occurred in both low-grade and high-grade lesions, with one high-grade case resulting in fatal metastases.
  • Standard pathologic criteria and flow cytometry showed poor correlation with recurrence risk.
  • Inadequate excision, even for small, low-grade tumors, was associated with recurrence.

Conclusions:

  • Phyllodes tumors display a broad spectrum of clinical behavior, from indolent to highly aggressive.
  • Surgical management, particularly the completeness of excision, is crucial for preventing recurrence.
  • Even small, low-grade phyllodes tumors necessitate thorough surgical removal to minimize the risk of recurrence and potential adverse outcomes.