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A new bastadin from the sponge Psammaplysilla purpurea
J R Carney1, P J Scheuer, M Kelly-Borges
1Department of Chemistry, University of Hawaii, Honolulu 96822.
Journal of Natural Products
|January 1, 1993
Abstract:
A new bastadin 2 and the previously reported bastadins 5 [3], 7 [4], and 12 (formerly bastadin 9) [5] were isolated from the Verongid sponge Psammaplysilla purpurea collected in Pohnpei. Compound 2 is mildly cytotoxic against several cell lines and inhibits the enzymes topoisomerase II and dehydrofolate reductase.