Hemoglobin M Oldenburg identified as HB alpha 2 87(F8)His replaced by Tyr beta 2

The abnormal hemoblobin designated as Hb M Oldenburg and already characterized as alpha 2 (72,87 or 89)His replaced by Tyr beta 2 was further identified by isolation, amino acid analysis and automated sequencing of the altered tryptic peptide alpha TIX. In this peptide the histidine in the position 87 is replaced by a tyrosine reside. Thus Hb M Oldenburg has to be described as alpha 2 87(F8)His replaced by Tyr beta 2 and is, therefore, identical with the mutant hemoblobins M Iwate and M Kankakee.