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Updated: Aug 14, 2026

In vitro Mesothelial Clearance Assay that Models the Early Steps of Ovarian Cancer Metastasis
Published on: February 17, 2012
Intermediate filaments in ovarian tumors
1Department of Pathology, Kaplan Hospital, Rehovot, Israel.
The availability in recent years of an ever increasing number of monoclonal antibodies to intermediate filaments which react with formalin-fixed, paraffin-embedded sections by the immunoperoxidase method, makes it possible to apply this technique in most surgical pathology laboratories. In addition to representing a major diagnostic tool that is often indispensable in the differential diagnosis, intermediate filaments typing of complex ovarian neoplasms has also shed some light on the histogenesis and differentiation potential of ovarian tumors.
The availability in recent years of an ever increasing number of monoclonal antibodies to intermediate filaments which react with formalin-fixed, paraffin-embedded sections by the immunoperoxidase method, makes it possible to apply this technique in most surgical pathology laboratories. In addition to representing a major diagnostic tool that is often indispensable in the differential diagnosis, intermediate filaments typing of complex ovarian neoplasms has also shed some light on the histogenesis and differentiation potential of ovarian tumors.
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